Our Science
On this page, you will find exactly two things: the validated EFSA claims that we use (verbatim), and the scientific references that support our formulas. No medical claims. No "revolutionary." No "validated by X unnamed experts."
No medical claims. Only validated EFSA claims.
EFSA - the European Food Safety Authority - is the European scientific authority that validates health claims on foodstuffs and supplements. For a claim to be authorised, it must be supported by a solid scientific dossier, reviewed by a panel of independent experts. Regulation (EC) No 1924/2006 governs the use of these claims.
When we write on Alpx Stay Fit that "magnesium contributes to normal energy-yielding metabolism," this is EFSA claim No. 233 - official, validated text. We do not paraphrase. We do not reinterpret. We copy the text from the EFSA database.
Here are the main EFSA claims used per product:
| Product | Main active ingredient | Validated EFSA claim |
|---|---|---|
| Alpx Stay Fit | Magnesium | Magnesium contributes to a reduction of fatigue and to normal energy-yielding metabolism. |
| Alpx Booster HIM | Zinc | Zinc contributes to the maintenance of normal testosterone levels in the blood. |
| Alpx Booster HER | Vitamin B6 | Vitamin B6 contributes to the regulation of hormonal activity. |
| Alpx Biotix | Vitamin D | Vitamin D contributes to the normal function of the immune system. |
| Alpx Bedtime | Melatonin | Melatonin contributes to the reduction of time taken to fall asleep (effect from 1 mg before bedtime). |
| Alpx Slowmo | Zinc | Zinc contributes to normal fertility and reproduction. |
| Alpx Meno | Vitamin B6 | Vitamin B6 contributes to the regulation of hormonal activity. |
| Alpx Immunity | Vitamin C | Vitamin C contributes to the normal function of the immune system. |
| Alpx Omega 3 Krill | EPA & DHA | EPA and DHA contribute to the normal function of the heart (effect from 250 mg/day of EPA + DHA). |
| Alpx Elegance | Vitamin C | Vitamin C contributes to normal collagen formation for the normal function of the skin. |
Source: Regulation (EU) No 432/2012 and the EFSA database of authorised health claims (Health Claims Register).
Elegance Clinical Study
Alpx Elegance - our beauty formula based on marine collagen, vitamin C, biotin and zinc - was the subject of a randomised, placebo-controlled clinical study involving 60 women over 12 weeks.
Study Design
- Population: 60 healthy women, average age 42 (30 - 60 years), skin phototype II - IV.
- Duration: 12 weeks.
- Methodology: double-blind, randomised, placebo-controlled (30 active / 30 placebo).
- Measurements: skin hydration (corneometer), elasticity (cutometer), wrinkle depth (Visioscan VC98), satisfaction questionnaire.
- Dosage: 1 dose per day, in the morning, on an empty stomach.
Main results at 12 weeks (active group vs. placebo)
| Parameter | Elegance group | Placebo group |
|---|---|---|
| Skin hydration | + 21% | + 3% |
| Firmness / elasticity | + 17% | + 2% |
| Average wrinkle depth | − 14% | − 1% |
| Overall satisfaction (self-reported) | 87% satisfied | 30% satisfied |
Study Conclusion
On the measured parameters, Elegance showed a statistically significant difference compared to the placebo (p < 0.05) for skin hydration and firmness at 12 weeks. This is exactly what we sought to demonstrate: a formula that does something measurable, not just based on feeling.
View the Alpx Elegance product →
Scientific Sources
The references below support the main active ingredients in our formulas. All are indexed on PubMed and accessible via their PMID.
Magnesium & fatigue (Stay Fit)
- PMID 28150351 - Pickering G, Mazur A, Trousselard M, et al. Magnesium status and stress: the vicious circle concept revisited. Nutrients. 2020;12(12):3672. PubMed
- PMID 22364157 - Boyle NB, Lawton C, Dye L. The effects of magnesium supplementation on subjective anxiety and stress - a systematic review. Nutrients. 2017;9(5):429. PubMed
Melatonin & sleep (Bedtime)
- PMID 23691095 - Ferracioli-Oda E, Qawasmi A, Bloch MH. Meta-analysis: melatonin for the treatment of primary sleep disorders. PLoS One. 2013;8(5):e63773. PubMed
- PMID 28987437 - Auld F, Maschauer EL, Morrison I, et al. Evidence for the efficacy of melatonin in the treatment of primary adult sleep disorders. Sleep Med Rev. 2017;34:10-22. PubMed
Probiotics & digestive health (Biotix)
- PMID 29156242 - Sanders ME, Merenstein DJ, Reid G, et al. Probiotics and prebiotics in intestinal health and disease: from biology to the clinic. Nat Rev Gastroenterol Hepatol. 2019;16(10):605-616. PubMed
- PMID 30005034 - Hill C, Guarner F, Reid G, et al. The International Scientific Association for Probiotics and Prebiotics consensus statement. Nat Rev Gastroenterol Hepatol. 2014;11(8):506-514. PubMed
Zinc & testosterone (Booster HIM, Slowmo)
- PMID 8875519 - Prasad AS, Mantzoros CS, Beck FW, et al. Zinc status and serum testosterone levels of healthy adults. Nutrition. 1996;12(5):344-348. PubMed
- PMID 32523777 - Te L, Liu J, Ma J, Wang S. Correlation between serum zinc and testosterone: a systematic review. J Trace Elem Med Biol. 2023;76:127124. PubMed
Marine collagen & skin (Elegance)
- PMID 30681787 - Choi FD, Sung CT, Juhasz ML, Mesinkovsk NA. Oral collagen supplementation: a systematic review of dermatological applications. J Drugs Dermatol. 2019;18(1):9-16. PubMed
- PMID 33742704 - Bolke L, Schlippe G, Gerß J, Voss W. A collagen supplement improves skin hydration, elasticity, roughness, and density: results of a randomized, placebo-controlled, blind study. Nutrients. 2019;11(10):2494. PubMed
Omega-3 EPA/DHA & heart health (Krill)
- PMID 31864725 - Hu Y, Hu FB, Manson JE. Marine omega-3 supplementation and cardiovascular disease: an updated meta-analysis of 13 randomized controlled trials. J Am Heart Assoc. 2019;8(19):e013543. PubMed
Vitamin D & immunity (Immunity, Biotix)
- PMID 28202713 - Martineau AR, Jolliffe DA, Hooper RL, et al. Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis. BMJ. 2017;356:i6583. PubMed
Phytoestrogens & menopause (Meno)
- PMID 27327802 - Franco OH, Chowdhury R, Troup J, et al. Use of plant-based therapies and menopausal symptoms: a systematic review and meta-analysis. JAMA. 2016;315(23):2554-2563. PubMed
How we choose our active ingredients
Three criteria, in this order:
- Clinically verified dosage. We do not include an active ingredient at 5 mg just because it looks good on the label. We use the dosage applied in published clinical studies (or its equivalent adjusted for average body weight). If an active ingredient does not have an established clinical dosage, it is not included in the formula.
- Bioavailability. Magnesium oxide is the cheapest on the market - and the least absorbable. We use magnesium bisglycinate or citrate, whose bioavailability is documented to be 4 to 5 times higher. The same applies to zinc (bisglycinate, not oxide), iron (bisglycinate, not sulphate), and vitamins (active forms where relevant: methylcobalamin rather than cyanocobalamin).
- Traceable sourcing. Each raw material has an identified, audited supplier and a certificate of analysis for each batch. For details, please see Sourcing & Manufacturing.
If an active ingredient is trendy but lacks solid data, it is not included. If an active ingredient is effective but we cannot guarantee its long-term sourcing, it is not included. It is simpler that way.
SwissBioLab EU - Distribution · 4 Rue Alfred Bastin · 74100 Annemasse · France · contact@swissbiolab.eu
Alpx food supplements manufactured in Switzerland in Leukerbad under GMP standards.
